Is the fallopian tube better than the uterus? Evidence on intrauterine insemination versus fallopian sperm perfusion
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چکیده
Fallopian tube sperm perfusion (FSP) is in short comprised of mild ovarian stimulation with the aim of maturing 2 follicles, ovulation induction and insemination using a large volume (4 ml) of inseminate. Perfusion studies demonstrated that with this large volume, the inseminate will fill the uterine cavity, flow through the fallopian tubes and some of it will end up in the peritoneal space. The rational being that this maximizes the chances the gametes will meet and fertilization occur. We initiated a prospective randomized study that showed that FSP gave higher pregnancy rates compared to conventional intrauterine insemination (IUI), OR: 4.1, (1.2-13.4 95% Confidence interval). In our hands, FSP seems to give the best results in couples with unexplained infertility. In the years 1990 to 2002, 1005 inseminations with husband’s semen were carried resulting in 141 pregnancies and 112 deliveries. In the same period, 1200 inseminations with frozen donor semen were carried out giving 333 pregnancies
منابع مشابه
The comparison between Intrauterine Insemination and Fallopian Tube Sperm Perfusion Using FAST
متن کامل
Questioning the efficacy of Fallopian tube sperm perfusion.
The aim of this work was to compare the efficiency of standard intrauterine insemination (IUI) and Fallopian tube sperm perfusion (FSP) in the treatment of infertility. Ninety-six consecutive patients with infertility in 100 cycles were included in the study. Those randomized to standard IUI included 48 patients in 50 cycles [25 clomiphene citrate only and 25 clomiphene citrate/human menopausal...
متن کاملThe comparison between Intrauterine Insemination and Fallopian Tube Sperm Perfusion Using FAST®System in Patients with Unexplained Infertility
BACKGROUND Controlled ovarian stimulation (COH) with intrauterine insemination (IUI) is commonly offered to infertile couples with patent fallopian tubes because it is simple, non-invasive and cost-effective technique. Another non-invasive method is fallopian tube sperm perfusion (FSP). This study was performed to compare the relative efficacy between FSP using fallopian sperm transfer (FAST) s...
متن کاملIntrauterine insemination versus Fallopian tube sperm perfusion in non-tubal subfertility: a systematic review based on a Cochrane review.
BACKGROUND The objective of this review was to compare the efficacy of Fallopian tube sperm perfusion (FSP) with intrauterine insemination (IUI) in the treatment of non-tubal subfertility. METHODS The principles of the Cochrane Menstrual Disorders and Subfertility Group were employed. Only randomized controlled studies comparing FSP with IUI were included in this review. The main outcome meas...
متن کاملA randomized controlled trial of fallopian tube sperm perfusion compared with standard intrauterine insemination for women with non-tubal infertility.
STUDY QUESTION Does fallopian tube sperm perfusion (FSP) result in better pregnancy and live birth rates than standard intrauterine insemination (SIUI) for couples with non-tubal infertility with or without gonadotrophin or clomiphene stimulation? SUMMARY ANSWER There was no evidence of an improvement in live birth rates with FSP compared with SIUI. WHAT IS KNOWN ALREADY Previous randomized...
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